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DataPlant is implementing Annotated Research Context (ARC), an RO-Crate profile that combines the Investigation Study Assay model (ISA) and the Common Workflow Language (CWL) to capture a range from single experimental setups to complex experimental designs.

In ARC, files are managed in a git repository with a fixed structure following the ISA model, in addition to metadata in an Excel spreadsheet. The arcCommander tool can help with managing this structure, while the tool arc–to-roc can inspect the structure to generate an RO-Crate metadata file. The ARC specification allows augmentation by adding an explicit ro-crate-metadata.json to the ARC.